Adie syndrome is a neurological disorder which affects the pupil of the eye and the autonomic nervous system. Adie's syndrome is caused by a viral or bacterial infection which causes inflammation leading to damage to the postganglionic fibers of the parasympathetic innervation of the eye. It is characterized by a tonically dilated pupil.
Adie syndrome presents with three hallmark symptoms, namely abnormal pupil size (mydriasis), loss of deep tendon reflexes which is permanent and may progress over time, and diaphoresis. Other signs may include hyperopia due to accommodative paresis, photophobia and difficulty reading.
Adie Syndrome is also sometimes known as Holmes-Adie's syndrome or Adie's Tonic Pupil